COLOSTRUM SURVIVES ADULT HUMAN DIGESTIVE TRACT AND WORKS ON MUCOSAL SURFACES:

Pineo, A. et. al. 1975 Biochemical Biophysiology Acta (Amsterdam.) 379: 201-206. Research by Drs. Pineo, Ortego, and Uriel in 1975 discovered a special glycoprotein in cow colostrum. They found it had "Protease Inhibitor Activity" that was extremely effective at protecting the immune and growth factors in colostrum from destruction by digestive acids pancreatic enzymes in the adult human stomach.

Sandholm et. al., Acta Veterinaria Scandinavica, 1980, Vol 20 No 4 pp 469-476. "Colostral Trypsin-Inhibitor Capacity in Different Animal Species": Bovine colostrum was found to contain a powerful trypsin-inhibitor which protects colostrum immunoglobulins from digestion. Demonstrated that colostrum from cows richer in immune factors and inhibitor than colostrum from humans.

Von Fellenberg, R. and Hoeber, 1980, Schweiz. Arch. Tierheilkd. Vol 122 No 3 pp 159-168. "Multiple Protease Inhibitors in Colostrum and In Bovine Udder Tissue and their Possible Significance": Protease inhibitors in colostrum shut down the digestive enzymes that would normally digest proteins such as the immunoglobulins, allowing them to remain active as they pass into the bowel.

Swarbrick, E. T. et. al.,. The Immunology of Infant Feeding, 1980, Plenum Press, NY, pp 13-20, "The Handling of Ingested Antigens": Dr. Swarbrick discovered that during the first 24-36 hours of a newborn’s life the bowel wall has a number of large open pores through which big immunoactive molecules from colostrum enter the system. Pages 55-61; Dr. David Tyrell; ‘Breast Feeding and Virus Infections’: "The major benefit of immune factors from colostrum was shown to be their protective activity in the intestine on the walls of the bowel, and bronchials, (mucosal surfaces). Conclusion: People of all ages may benefit from colostrum".

Hanson, et. al., Annals of NY Academy of Sciences, 409, 15ff: " Mucosal Immunity": The immune system produces immunoglobulins, antibodies, leukocytes, macrophages, interferon and other factors for defending the body. Immune factors from specialized cell groups in the bronchials and bowel travel away from their sources to coat the passages of the lungs and bowels and destroy antigens, allergens and pathogens. Immune factors from colostrum other than immunoglobulins blocked attachment of many types of bacteria to mucus membranes. Oligosacccharides (big sugar molecules) from colostrum blocked attachment of Streptococcus pneumonococci, a major cause of lung inflammations and middle ear infections.

Klapper, D. G.. et. al., 1983, Endocrinology; 112 (6) 2215-7. pp. 13-18: Oligo and polysaccharides in colostrum bind many types of bacteria and prevent them from attaching to or entering the body though the mucal membranes.

Bouda, et. al., 1987, Veterinari Medicina, Vol. 32 No 3 pp. 135-44: " Trypsin Inhibitor Activity in the Colostrum of Cows": Greatest Trypsin Activity was in the colostrum of the first milking after calving. (inhibitor effective in neutralizing digestive acids and enzymes in human digestive system to allow colostrum to reach intestinal area)

Preston, R., 1987, International Institute of Nutritional Research: "Bovine Colostum: Human consumption: Efficacy and effects: Found to be safe, effective via oral administration, no known contradictions or overdoses".

44. Ulcova-Gallova, Fialova, Krauz, 1994, Clinical Study: Cas Lek. Cesk. May 2, Vol. 133(9) pp. 275-6. Reported that: A. Immunofactors present in bovine colostrum are: IgG, IgM, IgA, sIgA, SCIgA, C3, C4, Orosormucoid, Prealbumin, Alpha 1- antitrypsin, Alpha-1 fetoprotein, Alpha-2-Macroglobulin, Alpha 2- AP Glycoprotein, and, IgE. B. An important immunological liquid with proven bacteriostatic and viral inhibitory activity preventing penetration of pathogenic microorganisms and absorption of potential allergens into the digestive tract.

Eldrige, et. al. 1983, Annals of NY Academy of Sciences, 409 pp. 819-821. "Peyer’s Patches accessory Cells Bear I-1": Groups of cells in the mucosa of the intestinal tract, known as Peyer’s patches produce and absorb immune factors.

Ogram Pearay, et. al., 1983, Annals of NY Academy of Sciences, 409, pp 82-92: "Colostrum Derived Immunity and Maternal Neonatal Interaction": Peyer’s patches are found throughout the intestinal tract and groups of immunoactive cells like them are found in the bronchial mucosa. Both the intestinal and bronchial immunoactive cell groups respond to allergens, antigens and pathogens by neutralizing or destroying them. In newborns, these special cell groups are not immediately operative but protection is provided by a variety of immune factors from the mother’s colostrum. Antibodies found in colostrum protect against E. coli, Salmonella, Shigella, V. cholera, Bacteriodes Fragilis, Streptococcus Pneumoniae, Bordtella Petussis, Clostridium diphtheria, Clostridium Tetani, Streptococcus Mutans and Candida albicans.

Waldman, et. al., 1983, Annals of NY Academic Science, Vol. 409, 510-515: Reported the intestinal tract is lined with mucous membranes. Researchers at West Virginia University School of Medicine and Pharmacy stated: " Most infectious diseases enter the body through or remain localized on mucosal surfaces." Waldman stated: "that this means in order to be healthy, we must be able to combat disease causing organisms where most of them attack us; which is on the mucous membranes of the intestinal tract." (this is where colostrum does most of its work).

Dial, Elizabeth J.; et al. Gastroenterology, 87; 379-85, 1984 A Role for Milk Phospholipids in Protection Against Gastric Acid (Studies in Adult and Suckling Rats. Findings suggest that milk contains potent anti-ulcer activity.

Kivinen, Anneli; S. Salminen; et al. Milchwisser schaft, 47(9), 1992. Gastroprotective effect of milk phospholipids, butter serum lipids and butter serum on ethanol and scetylsalicylic acid induced ulcers in rats. Phopholipids in cow milk protect the GI tract from ulcers.

Service, Science, Sept 9, 1994 v 265 p 1522-4: Research News: Triggering the First line of Defense: " Vaccines that activate the mucosal immunity, the bodies first chance to ward off infection, are hard to come by. Situation changing, new vaccines are needle free. Mucosal surfaces turn out 70% of our body’s antibodies. Has been virtually ignored. Mucosal system most important area to concentrate attention in prevention of disease. New vaccines developed to be delivered orally. IgA very effective in picking up invaders before they gain entry. Studies prove that vaccines made with pathogens that infect animals can confer protection to humans."

Science News: Vol. 133 pp. 196, 1994: Colostrum and breast milk (from cows, sheep and humans) stimulates babies own immune systems: as yet unidentified proteins speed the maturation of cultured B lymphocytes (a type of white blood cell) and prime them for production of antibodies says: Michael Julius Of McGill University, Montreal.

Pakula, Ronit; et al. Lipids, Vol. 31, no. 3, 1996. The Effects of Dietary Phospholipids Enriched with Phosphatidylethanolamine on Bile and Red Cell Membrane Lipids in Humans. Diets enriched in phospholipids resulted in reduced cholesterol saturation in the bile with no side effects.

Litman, Burton J.; et al. Lipids, Vol 31, Supplement, 1996. A Role for Phospholipid Polyunsaturation in Modulating Membrane Protein Function.